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KMID : 0370220210650060481
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Yakhak Hoeji
2021 Volume.65 No. 6 p.481 ~ p.486
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A Study on the Effects of Climate Change Factors on the Adverse Drug Event (ADE) Reports Focusing on Diarrhea and Respiratory Diseases
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Lee Sung-Hyun
Jang Bo-Won
Lee Yeun-Kum
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Abstract
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The relationship between diarrhea and respiratory disorders and climate change has been previously elucidated.
Diarrhea and respiratory diseases have been reported to the Korea Institute of Drug Safety and Risk Management (KIDS)as adverse drug events (ADEs) and as serious adverse events (SAEs) due to the occurrences of hospitalization, death, andmalformations. ADEs are reported by patients, hospitals, clinics, pharmacies, manufacturers (importers), and regional drugsafety centers. However, it has not been determined that the reported adverse events of diarrhea and respiratory diseasesare caused by whether climate change or drugs. Here, we investigate the number of ADEs of diarrhea and respiratorydiseases that were reported to the Korea Institute of Drug Safety and Risk Management (KIDS) from September 1, 2012to October 4, 2020, and analyze them with respect to climatic factors including average temperature, daily precipitation,relative humidity, and fine dust concentration (PM10, PM2.5). Our findings suggest that none of the climate changevariables are statistically associated with the reported ADEs or SAEs, and climate change has no effect on the number ofreported ADEs and SAEs.
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KEYWORD
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Adverse drug event, Diarrhea disease, Respiratory disease, PM10/PM2.5 density, Weather factor
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